Original article:
https://doi.org/10.1038/s41467-024-48017-6This is the best summary I could come up with:
The authors concluded that some of these proteins could be used to detect cancer much earlier and potentially provide new treatment options, though further research was needed.
Dr Keren Papier, a senior nutritional epidemiologist at Oxford Population Health at the University of Oxford and joint first author of the study, said: “To save more lives from cancer, we need to better understand what happens at the earliest stages of the disease … [and] how the proteins in our blood can affect our risk of cancer.
While altering these proteins may increase or decrease the chances of someone developing cancer, in some cases this could lead to unintended side-effects, the authors found.
Mark Lawler, the chair in translational cancer genomics and professor of digital health at Queen’s University Belfast, said: “The data are impressive – finding evidence of cancer before it has manifested itself clinically provides a critical window of opportunity to treat with a greater chance for success, or even more importantly to achieve the holy grail of preventing cancer before it can even occur.
More work to be done, but an important step forward in a disease that affects one in two of UK citizens during their lives.”
“Determining protein changes that precede the development of cancer is not only important in identifying high-risk individuals but could also provide insights into factors responsible for causing cancer.”
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