anathema (plural anathemas or anathemata)

1. (ecclesiastical, historical) A ban or curse pronounced with religious solemnity by ecclesiastical authority, often accompanied by excommunication; something denounced as accursed. [from early 17th c.]
   Synonyms: ban, curse
2. (by extension) Something which is vehemently disliked by somebody.
   Synonyms: antipathy, bête noire, bugbear
3. (literary) An imprecation; a curse; a malediction.
4. (ecclesiastical) Any person or thing anathematized, or cursed by ecclesiastical authority to unending punishment.