Everything can go wrong in one way or another, it just depends how high the risk is. People drive their car every day, even if there is a chance that they wont make it to the next day because of it.

But the risk just isnt felt to be too high in comparison to the usefulness, or people wouldnt drive.

If I knew that it was fairly safe to go to the moon, I would do it, even if it could mean that I dont come back, because it would be a pretty special experience.