Thank you for linking her talk about the paper! It gives it so much more context. It’s clear now that they studied a cohort who had already developed some brain network instability, and used exogenous ketones to induce ketosis in the participants. Dr. Lily does mention a ketogenic diet as a means to get into ketosis as well.
Nick Norwitz found that plaque predicts more plaque, but this seems to offer some hope that it’s possible to reverse some of that with diet. It’s curious that some of the quantitive analysis would have conflicting results, though.
Can’t wait for the year of the vibe coded OS.
Isotopic testing shows that early humans primarily subsisted on herbivores and small game, including fish. Please refer to this study for Europe.
Early modern humans also appear to have regularly hunted large herbivores (55–57), but there is also evidence for the use of small game, including fish at some of these sites (15, 16).
Or this study, also from Nature, again studying the first modern humans and late Neandertals in Europe:
based on stable isotopes, the mammoth seems to contribute the major part of the dietary protein of humans in a time range between 50,000 and 30,000 years ago and across wide areas spanning from SW France11 to the Crimean Peninsula53 (Fig. 6, Supplementary Fig. 5–8).
It is inaccurate to state that humans did not eat much meat prior to modern times.
Next time I meet up with my mouse friends I’ll be sure to let them know.
Dr. Norwitz has very high “self experimenting mad scientist” energy.
One possible thing that may account for some increase in my LDL is that I only started avoiding industrially processed seed oils when I started LCHF, prior to that even though I was eating whole foods I did not try to avoid seed oils. I would also eat deep-fried meats, like tonkatsu or kushiage.
Thank you for doing that for me!
have you been increasing physical activity in the different phases?
Yes, I now walk about twice as much as I used to daily. Starting from being diagnosed with NAFLD I started running and morning calisthenics. Prior to that I used to swim every day, but Covid stopped that and I did not resume swimming after.
have you been getting stronger? Any new PRs, or endurance changes?
Yes, I’ve been gradually increasing the amount of daily calisthenics I do in the morning. Recently I’ve gone from about 25 push-ups a day to 35.
do you have a standardized training program? Or was the effect all from diet?
I do, I do about 30 minutes of calisthenics in the morning. The McGill Big 3, planks, pushups, and a bunch of stretches. I used to run every other day but have switched that out for more walking.
Forgot to address fasting insulin. I can’t get that test here from my medical checkup provider, for some reason, I’ll have to ask my GP for it.
whole food? Fasted readings?
Yes to both.
Tg
It surprised me also. Maybe it’s because I’m not eating enough fat and too much protein, and it’s being converted into glucose. I’ll try increasing my fat intake some.
Bart Kay
Seems like he’s also moved off YouTube to Odysee, maybe to avoid being shadowbanned by Google.
Based on your lipids before you started this eating pattern: improved, stayed the same, gotten worse ?
I have yearly medical test records, which I have annotated. In the year prior to being diagnosed with NAFLD I tried going fully plant-based. Prior to starting carnivore, I only ate in a 8 hour window for about 15 years.
| 2025/08/25 | 2025/07/22 | 2024/08/07 | 2023/08/25 | 2022/08/30 | |
|---|---|---|---|---|---|
| Notes | Today | Start of carnivore | Start of LCHF Keto | Start of no refined carbs, no sugars | NAFLD, start of no sugar |
| Weight, Kg | 59.1 | 63.6 | 66.9 | 76.3 | 78.2 |
| BMI | 19.4 | 20.8 | 22.1 | 25.0 | 25.6 |
| Abdominal Girth/Height | No data | 0.43 | 0.49 | 0.49 | 0.54 |
| LDL, mg/dl | 212 | 183 | 107 | 152 | 149 |
| HDL, mg/dl | 66 | 63 | 61 | 55 | 48 |
| Triglycerides, mg/dl | 98 | 66 | 58 | 112 | 181 |
LDL has gone up progressively, but my lipids have improved in general. I’m curious about how they will look in a year on carnivore, then two years or three years down the line.
Statins, CAC
That’s a good idea. I’m slightly concerned about the radiation dosage so I’ll only do it if I feel like I’m at risk. I’ll definitely keep it in mind. I had no intention of taking statins at all, so I declined to do so in the nicest way I could.
friend pushback
Not really, they’ve seen my changes physically and have asked me how I did it. I’m still not sure how far I can go and not have them feel any social pressure. I will buy a couple CGMs!
temptation
I ate pizza, then had tiramisu for dessert and drank some wine last weekend and I definitely felt like I succumbed. The temptation is very real especially when it’s with people whose company I enjoy.
Bart Kay
He’s my favourite of all the carnivore doctors when he’s not being a shock jockey! haha
In terms of emotional wellbeing, I feel really good. I’m not sure how to put it into words, but I find myself quicker to smile, for example.
For physical wellbeing, besides the occasionally scratchy eyes in the morning (still no idea what it is but it doesn’t hurt, just odd to have dry-eye in summer) I’m the best I’ve been as well. I feel energized and vigorous, and I have a lot of energy. I can walk up the hill to work without any fatigue, whereas just a year before I’d feel a little tired by the time I reach the top. It’s a lot of little things.
Word of mouth existed long before advertising, and as for algorithmic discoverability retailers do a fine job of that already.
Reminded me of my university’s stats lectures, but with the technical bits boiled down to simplified abstractions instead of 1 hour sessions with the TAs.
“It’s my ccomputer” has already been mentioned, but it’s my bandwidth and my home network too. Ads can stay off it.
I know that this is mentioned in videos from Low Carb Down Under by Dr Mason, among others, but for visitors just browsing the comments, I’d like to quote
Nevertheless, the IARC working group concluded that for every 50 grams of processed meat eaten, the relative risk of colon cancer was increased by 18% compared with those who ate the least processed meat. How does this compare with known carcinogens? The increased relative risk of lung cancer from smoking cigarettes is 1000–3000%. The increased relative risk of liver cancer from eating moldy grains contaminated with aflatoxin is about 600%. In fields outside nutrition, the usual threshold for confidence about relative risk is in the range of 200–400%. At the higher end of that range, one can be guardedly confident but “we can hardly ever be confident about estimates of less than 2.0, and when estimates are much below 2.0, we are simply out of business” (Shapiro, 2004); relative risk of 2.0 translates to an increase of 100%. So, an 18% increase equals a relative risk of 1.18, and this score falls substantially below the threshold that epidemiologists in other fields generally accept as worthy of further investigation.
Another indicator of risk is the absolute risk, as opposed to the previously mentioned relative risk. The relative risk is a ratio of the disease rate in the group exposed to the highest amount divided by the rate in the group exposed to the lowest amount but this risk ratio does not reflect the absolute risk of a disease. The lifetime absolute risk of colon cancer in vegetarians is 4.5 out of 100; in people eating 50 grams of processed meat every day for a lifetime, the risk is 5.3 out of 100. These numbers are not statistically distinguishable in epidemiological studies.
Emphasis mine.
Fundamentally, the concept that your computer can actually look at your screen and is context aware is going to become an important modality for us going forward.”
Since I don’t feel the need for ambience nor multi-modal experiences in my OS, considering the implementation of that “modality” I’m afraid that even as a long-time Windows user I’m going to have to switch to another OS that closer aligns to my needs.
How often do you go?
I find that remarkable considering the fact that astronauts would eat high protein foods to minimize their bowel movements because the human body will efficiently absorb highly bioavailable proteins and fat (e.g. from animal sources) it consumes. Considering human feces are 75% water and the remaining 25% are primarily bacterial biomass and plant matter, my guess is the carnivores you know have just started the diet and have upset their stomachs with the sudden change.